Christina Applegate‘s representative has responded to a report that the actress has been hospitalized amid her battle with multiple sclerosis (MS).
TMZ reported on Thursday, April 16, that the Married… With Children alum, 54, is currently in a Los Angeles hospital after being admitted in late March. It is unclear whether her reported hospitalization is due to her MS.
Applegate’s rep later said in a statement to Us Weekly, “I have no comment whether she is in the hospital or what her medical treatments are. She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”
Applegate has been candid about her battle with MS since she publicly revealed her diagnosis in August 2021.
“It’s been a strange journey,” she wrote via X at the time. “But I have been so supported by people that I know who also have this condition. It’s been a tough road. But as we all know, the road keeps going. Unless some a**hole blocks it.”
Christina Applegate. (Photo by John Shearer/Getty Images)
Speaking to Variety in November 2022, Applegate recalled experiencing symptoms while filming Netflix’s Dead to Me.
“I didn’t know what was happening to me. That January, my toes got numb, and I ignored it. The balls of my foot got numb, and I ignored it. All of a sudden, I’d be, like, falling over,” she explained. “People were like, ‘Oh, it’s just neuropathy.’ At this point, they had to take me with a wheelchair to set because I couldn’t walk if the set was far. I was sleeping all the time, and I gained 40 pounds — a lot of things happened.”
Christina Applegate. (Photo by Axelle/Bauer-Griffin/FilmMagic)
In January 2026, she detailed a recent flare-up and expressed her fears that MS may be “taking” her.
Applegate got emotional during an episode of her “MeSsy” podcast, which she cohosts with Jamie-Lynn Sigler, who also has MS.
Christina Applegate is reflecting on her recent rare outing to the Married With Children reunion. “It was at the Wiltern theater in Los Angeles. A couple thousand folk there,” Applegate, 54, said during the Tuesday, February 10, episode of her and Jamie Lynn Sigler’s “MeSsy” podcast, recalling the January 28 event titled “An Evening With […]
In the emotional moment, Applegate read a letter from a fan named Steven, who suffers from myasthenia gravis (MG). The autoimmune disease causes weakness in certain voluntary muscles. Steven wrote that MG has “taken [his] soul piece by piece, day by day, hour by hour,” which reminded Applegate of a recent MS flare-up.
“I’m reading it and I’m trying not to start being a crybaby again with every single thing that I’m reading, because I’m getting very emotional because I’m really touched by the fact that we’re all sitting in that space,” she said. “Like yesterday, I was walking, kind of OK. … Today, I was falling over, stumbling. I just feel like, is it taking me? Is it taking me day by day, piece by piece? I can’t even read s*** like this without getting super highly triggered.”
