MLB Best Bets: Jacob Misiorowski, Dylan Cease Lead Monday’s Top Picks

Fatigue time is over for Jacob Misiorowski as the All-Star right-hander steps on the mound for the first time since July 7 when the Milwaukee Brewers face the visiting New York Mets on Monday night. Misiorowski missed his final start before the All-Star break due to a tired pitching arm and he also sat out the All-Star Game.

Misiorowski is one of the top pitchers in the National League and the Brewers will be a trendy postseason pick if the 24-year-old fireballer is healthy. It will be interesting to see if he is on a pitch count against the Mets.

Dylan Cease of the Toronto Blue Jays took a no-hitter into the ninth inning in his last start and he will look to silence the Tampa Bay Rays. We’ll also look at the Cincinnati Reds visiting the Seattle Mariners.

NEW YORK METS AT MILWAUKEE BREWERS

Misiorowski is 10-4 over 18 starts and leads the majors with 167 strikeouts and a 1.62 ERA while throwing 111 innings, close to last year’s combined 129 1/3 innings between the minor leagues and the Brewers. Those pitches that reach 105 mph put a lot of stress on the arm and his long-term chances of avoiding a serious arm injury are a constant fear to the Brewers.

Misiorowski has fanned 10 or more batters eight times this season as he tries to silence the New York bats that sit 25th in the majors with just 409 runs scored. Juan Soto is batting .290 with 21 homers and 52 RBIs but Francisco Lindor has played in just 43 games due to injuries and has just six blasts and 15 RBIs.

Free-agent signee Bo Bichette has been a bust for the Mets with a .253/.300/.370 slash line and trade acquisition Marcus Semien is hitting just .207. It is hard seeing New York doing much against The Miz as its miserable season continues.

Jacob Misiorowski to strike out 10 or more batters, +134 (DraftKings)

TAMPA BAY RAYS AT TORONTO BLUE JAYS

Cease ranks second in the majors with 148 strikeouts and also fanned three in his one inning as American League starter and winning pitcher in the All-Star Game. He finished play before the break with 15 shutout innings in which he allowed four hits and struck out 20.

He put up a great performance while chasing his second career no-hitter against the San Francisco Giants on July 8 before Heliot Ramos led off the ninth with a solid single to center. Toronto has been a disappointment after losing in the World Series last year and sits in last place in the AL East heading into its 100th game of the season.

The Rays own the best record in the AL but have lost a season-worst five straight games so another Cease gem is possible. Tampa Bay will look for All-Star Nick Martinez to continue a strong season in which he has issued just 19 walks in 18 starts.

Teams to combine for under 7.5 runs, -115(DraftKings)

CINCINNATI REDS AT SEATTLE MARINERS

The Mariners have won consecutive games to get back to .500 but have been season-long underachievers after losing to Toronto in seven games in the American League Championship Series last season. Seattle has guys named Cal Raleigh, Julio Rodriguez, Josh Naylor and Randy Arozarena on the roster but you will find surprise team leaders like Luke Raley (15 homers) and Cole Young (48 RBIs).

Raleigh has collapsed this season with a .163 average, nine homers and 29 RBIs after his monster 2025 season that included 60 homers and a second-place finish in the AL MVP race. Cincinnati is eight games under .500 and close to falling out of the National League wild-card chase in what would be a disappointing development after landing a wild-card spot last season.

Reds left-hander Andrew Abbott (5-5, 4.11) is having the worst of his four big league seasons but he’s capable of going on a strong finishing kick. He should find pitching in Seattle much to his liking despite losing in his lone appearance in the ballpark in 2024 when he gave up two runs on four hits over six innings, including homers to Raleigh and Mitch Garver.

Reds to win via Moneyline, +129 (DraftKings)