It’s been over seven years since CBS’s “The Big Bang Theory” ended, with multiple spin-offs following. Recently, Mayim Bialik appeared in the newest series set in the show’s universe, “Stuart Fails to Save the Universe.” Following the much-buzzed-about appearance on the HBO Max series, the “Blossom” alum is opening up about where she stands with the cast.
Bialik interviewed with PEOPLE in August 2026, discussing her recent appearance on “Stuart Fails to Save the Universe,” which featured cameos from several other actors from the original series, including Kaley Cuoco. Regarding her status with her former co-stars, she said, “I guess I’m closest with John Ross Bowie.” For context, he portrayed Barry Kripke on the beloved show.
She also mentioned Kevin Sussman, who stars in the newest spin-off of “The Big Bang Theory.” According to her, “I have such respect for Kevin Sussman and the work that we got to do together and just watching how he takes direction and how he so effortlessly has stepped into the role of leading man.”
The actress continued, “I worked with Lauren [Lapkus] and Brian [Posehn]’s been on our podcast, so I have other connections, but in terms of the emotional connection, I like being able to reach out to John and to Kevin and to be able to say, ‘I do not have any memory in my career of being this excited for another actor.”
Mayim Bialik Also Spoke About Her Relationship With Melissa Rauch
During the conversation, Bialik also opened up about the deep respect for the cast, especially Melissa Rauch, who played Bernadette Rostenkowski-Wolowitz on the show. Notably, she also shared that they had an encounter behind the scenes of “Stuart Fails to Save the Universe.”
According to Bialik, “I’m very close with Melissa Rauch. So she and I talked the most about scheduling and things like that. Regarding their recent encounter, she shared, “We were actually able to physically connect on set, me and Melissa. I can’t remember if she was there for a wardrobe fitting, and it was my filming day. I don’t remember, but that was really, really special.”
From there, Bialik went on to note the impact of their respective roles on “The Big Bang Theory.” She explained, “Bernadette, the character of Bernadette, was a microbiologist on ‘The Big Bang Theory.’ We were two women in science, both with very different personalities, very different aesthetics.”
The former “Jeopardy” host continued, “And we both represented as equally competent, fun, interesting people. I think that’s actually the truth about a lot of people in science, and in particular, a lot of women in science.”
‘The Big Bang Theory’ Ended In 2019
“The Big Bang Theory” premiered on CBS in 2007 and ran for 12 seasons, ending in 2019 after 279 episodes. Since then, three spin-off series have aired, starting with “Young Sheldon,” which concluded in May 2024 after seven seasons. Now, season three of “Georgie & Mandy’s First Marriage” begins in October, and “Stuart Fails to Save the Universe” has already been renewed for a second season.
During her PEOPLE interview, Bialik opened up about returning for the newest show. She said, “I would’ve been happy to come back as any iteration of anything. Just to get to be part of the Chuck Lorre universe and also to do this with Kevin and John and with Lauren and Brian, so I would’ve been happy literally to do anything.”
Mayim Bialik Shared Sad News About The Planned ‘Blossom’ Reboot In 2025
Before “The Big Bang Theory,” the world got to know Bialik through the 1990s sitcom “Blossom.” Regarding the planned reboot, Bialik revealed in 2023 that a script had been written and that the original cast had interest in returning for the series. She later stated that the new version might not be a sitcom, as the original show was.
However, according to The Wrap, she said in August 2025 that Disney, which retains the rights to “Blossom,” decided not to move forward with the series. She said the company’s change of heart came after it showed interest in the show the year before.
She said on Substack, “We will likely never know … why they would not let us bring these beautiful stories to people who love 90s nostalgia and who have a special place in their hearts for Blossom.”
Mayim Has A New Movie In The Works
Deadline reported in August 2025 that Bialik had been cast in an upcoming rom-com, “Go-Love-Go,” alongside her former “Call Me Kat” co-stars Cheyenne Jackson and John Griffin. Notably, Griffin not only stars in the movie, but he also wrote and produced it.
Currently, IMDb lists the film as in post-production, with no release date announced.
